[Assessment of self-reported cardiovascular and metabolic diseases in the German National Cohort (GNC, NAKO Gesundheitsstudie): methods and initial results].

Titel[Assessment of self-reported cardiovascular and metabolic diseases in the German National Cohort (GNC, NAKO Gesundheitsstudie): methods and initial results].
MedientypJournal Article
Jahr der Veröffentlichung2020
AutorenJaeschke L, Steinbrecher A, Greiser KHalina, Dörr M, Buck T, Linseisen J, Meisinger C, Ahrens W, Becher H, Berger K, Braun B, Brenner H, Castell S, Fischer B, Franzke C-W, Gastell S, Günther K, Hoffmann W, Holleczek B, Jagodzinski A, Kaaks R, Kluttig A, Krause G, Krist L, Kuß O, Lehnich A-T, Leitzmann M, Lieb W, Löffler M, Michels KB, Mikolajczyk R, Peters A, Schikowski T, Schipf S, Schmidt B, Schulze M, Völzke H, Willich SN, Pischon T
JournalBundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
Datum der Veröffentlichung2020 Mar 10
ISSN1437-1588
Zusammenfassung

BACKGROUND: Data on self-reported cardiovascular and metabolic diseases are available for the first 100,000 participants of the population-based German National Cohort (GNC, NAKO Gesundheitsstudie).

OBJECTIVES: To describe assessment methods and the frequency of self-reported cardiovascular and metabolic diseases in the German National Cohort.

MATERIALS AND METHODS: Using a computer-based, standardized personal interview, 101,806 participants (20-75 years, 46% men) from 18 nationwide study centres were asked to use a predefined list to report medical conditions ever diagnosed by a physician, including cardiovascular or metabolic diseases. For the latter, we calculated sex-stratified relative frequencies and compared these with reference data.

RESULTS: With regard to cardiovascular diseases, 3.5% of men and 0.8% of women reported to have ever been diagnosed with a myocardial infarction, 4.8% and 1.5% with angina pectoris, 3.5% and 2.5% with heart failure, 10.1% and 10.4% with cardiac arrhythmia, 2.7% and 1.8% with claudicatio intermittens, and 34.6% and 27.0% with arterial hypertension. The frequencies of self-reported diagnosed metabolic diseases were 8.1% and 5.8% for diabetes mellitus, 28.6% and 24.5% for hyperlipidaemia, 7.9% and 2.4% for gout, and 10.1% and 34.3% for thyroid diseases. Observed disease frequencies were lower than reference data for Germany.

CONCLUSIONS: In the German National Cohort, self-reported cardiovascular and metabolic diseases diagnosed by a physician are assessed from all participants, therefore representing a data source for future cardio-metabolic research in this cohort.

DOI10.1007/s00103-020-03108-9
Alternate JournalBundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
PubMed ID32157352